Baumann Research Group

44. “Unprecedented Alkene Transposition in Phthalate-Amino Acid Adducts” I. Saha, I.R. Baxendale,* M. Baumann* Synlett 2018, 29, 2648.

43. “Diastereoselective Synthesis and Diversification of Highly Functionalised Cyclopentanones” M. Baumann,* I.R. Baxendale Synthesis 2018, 50, 753-759.

42. “Flow Chemistry Approaches Applied to the Synthesis of Saturated Heterocycles”. In: Topics of Heterocyclic Chemistry, Springer, Berlin, Heidelberg, 2018. M. Baumann and I. R. Baxendale.

41. “A Concise Flow Synthesis of Indole-3-carboxylic Ester and its Derivatisation to an Auxin Mimic” M. Baumann, I.R. Baxendale,* F. Deplante Beilstein J. Org. Chem. 2017, 13, 2549-2560.

40. “A Sustainable Flow Synthesis of a Versatile Cyclopentenone Building Block” M. Baumann, I.R. Baxendale,* P. Filipponi, T. Hu Org. Process Res. Dev. 2017, 21, 2052-2059.

39. “Ethyl 5-(4-bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate” M. Baumann, I.R. Baxendale* Molbank 2017, M951.

38. “Rac-2’,3a,6,6,6’,6’-hexamethyl-3a,3b,6,7-tetrahydrospiro-[benzo[2,3]cyclopropane[1,2-c]pyrazole-1,1’-cyclohepta[2,4]diene] M. Baumann, S. Lapraille, I.R. Baxendale* Molbank 2017, M948.

37. “Flow Assisted Synthesis: A Key Fragment for SR142948A” M.O. Kitching, O.E. Dixon, M. Baumann, I.R. Baxendale* Eur. J. Org. Chem. 2017, 44, 6540-6553.

36. “A Continuous Flow Method for the Desulfurization of Thioimidazoles Applied to the Synthesis of New Etomidate Derivatives” M. Baumann,* I.R. Baxendale Eur. J. Org. Chem. 2017, 44, 6518-6524.

35. “A Continuous Flow Synthesis and Derivatization of 1,2,4-Thiadiazoles” M. Baumann,* I.R. Baxendale Bioorg. Med. Chem. 2017, 25, 6218-6223.

34. “Diastereoselective Trifluoroacetylation of Highly Substituted Pyrrolidines by a Dakin-West Process.”
M. Baumann,* I.R. Baxendale J. Org. Chem. 2016, 81, 11898-11908.

33. “Exploring Flow Procedures for Diazonium Formation.”
T. Hu, I.R. Baxendale*, M. Baumann Molecules 2016, 21, 918.

32. “Continuous Flow Synthesis of 2H-Azirines and their Diastereoselective Transformation to Aziridines.”                      
M. Baumann*, I.R. Baxendale Synlett 2016, 27, 159-163.

31. “Continuous Photochemistry: The Synthesis of Ibuprofen via a Photo-Favorskii Rearrangement.”                                
M. Baumann, I.R. Baxendale* React. Chem. Eng. 2016, 1, 147-150.

30. “Synthesis of 1,3,6-Trisubstituted Azulenes.” 
T.O. Leino*, M. Baumann, J. Yli-Kauhaluoma, I.R. Baxendale, E.A.A. Wallén J. Org. Chem. 2015, 80, 11513-11520.

29. “The Synthesis of Active Pharmaceutical Ingredients (APIs) using Continuous Flow Chemistry.”                                    
M. Baumann*, I.R. Baxendale* Beilstein J. Org. Chem. 2015, 11,1194-1219.

28. “Batch and Flow Synthesis of Pyrrolo[1,2-a]quinolines via an Allene-Based Reaction Cascade.”                                       
M. Baumann, I.R. Baxendale* J. Org. Chem. 2015, 80, 10806-10816.

27. “Tricyclic Analogs of Epidithiodiketopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity.”
M. Baumann, A.P. Dieskau, B.M. Loertscher, M. Walton, S. Nam, J. Xie, D. Horne*, L.E. Overman* Chem. Sci. 2015, 6, 4451-4457.

26. “Flow Synthesis of Ethyl Isocyanoacetate Enabling the Telescoped Synthesis of 1,2,4-Triazoles and Pyrrolo-[1,2-c]pyrimidines.”
M. Baumann, A.M. Rodriguez Garcia, I.R. Baxendale* Org. Biomol. Chem. 2015, 13, 4231-4239.

25. “Syn-Ethyl 1-Hydroxy-7-methoxy-2,3-dihydro-1H-pyrrolo[3,4-b]quinoline-3-carboxylate HCl Salt.”                             
M. Baumann, I.R. Baxendale* Molbank 2015, 1, M846.

24. “Boehmeriasin A as a New Lead Compound for the Inhibition of Topoisomerases and SIRT2”
M.S. Christodoulou, F. Calogero, M. Baumann, A.N. Garcia-Argaez, S. Pieraccini, M. Sironi, F. Dapiaggi, R. Bucci, G. Broggini, S. Gazzola, S. Liekens, A. Silvani, M. Lahtela-Kakkonen, N. Martinet, A. Nonell-Canals, E. Santamaria-Navarro, I.R. Baxendale, L. Dalla Via, D. Passarella* Eur. J. Med. Chem. 2015, 92, 766-775.

23. “Sustainable Synthesis of Thioimidazoles via Carbohydrate-Based Multicomponent Reactions.”                                   
M. Baumann, I.R. Baxendale* Org. Lett. 2014, 16, 6076-6079.

22. “Synthesis of Riboflavines, Quinoxazolinones and Benzodiazepines through Chemoselective Flow Based Hydrogenations.”
M. Baumann, I.R. Baxendale*, C.H. Hornung, S.V. Ley, M.V. Rojo, K.A. Roper Molecules 2014, 19, 9736-9759.

21. “The Rapid Generation of Isothiocyanates in Flow”
M. Baumann, I.R. Baxendale* Beilstein J. Org. Chem. 2013, 9, 1613-1619.

20. “An Overview of the Synthetic Routes to the Best-Selling Drugs Containing 6-Membered Heterocycles”
M. Baumann*, I.R. Baxendale* Beilstein J. Org. Chem. 2013, 9,2265-2319.

19. “Synthesis of (–)-Hennoxazole A: Integrating Both Batch and Flow Chemistry Methods”
A. Fernández, Z.G. Levine, M. Baumann, S. Sulzer-Mossé, C. Sparr, S. Schläger, I.R. Baxendale, S.V. Ley* Synlett 2013, 514-518.

18. “Scale-up of Flow-assisted Synthesis of C2-Symmetric Chiral PyBox Ligands”
C. Battilocchio, M. Baumann, I.R. Baxendale, M. Biava, M.O. Kitching, S.V. Ley, R.E. Martin*, S.A. Ohnmacht, N.D.C. Tappin Synthesis 2012, 635-647.

17. “A New Enabling Technology for Convenient Laboratory Scale Continuous Flow Processing at Low Temperatures”
D.L. Browne, M. Baumann, B.H. Harji, I.R. Baxendale, S.V. Ley* Org. Lett. 2011, 13, 3312-3315.

16. “A Flow-Based Approach for the Synthesis of O-Methyl Siphonazole”
M. Baumann, I.R. Baxendale, M. Brasholz, J.J. Hayward, S.V. Ley, N. Nikbin Synlett 2011, 1375-1380.

15. “Synthesis of a Drug-Like Focused Library of Trisubstituted Pyrrolidines in Flow” M. Baumann, R.E. Martin*, C. Kuratli, J. Schneider, I.R. Baxendale, S.V. Ley ACS Combinatorial Science 2011, 13, 405-413.

14. “An Overview of the Key Routes to the Best Selling 5-Membered Ring Heterocyclic Pharmaceuticals.”                              
M. Baumann*, I.R. Baxendale*, S.V. Ley*, N. Nikbin* Beilstein J. Org. Chem. 2011, 7, 442-495.

13. “Flow Synthesis of Heterocycles for Natural Product and Medicinal Chemistry Applications”
M. Baumann*, I.R. Baxendale, S.V. Ley Molecular Diversity 2011, 15, 613-630.

12. “Synthesis of Highly Substituted 3-Nitropyrrolidines and 3-Nitropyrroles by a Multicomponent-Multistep Flow-Sequence”
M. Baumann, I.R. Baxendale, A. Kirschning, S.V. Ley*, J. Wegner, Heterocycles 2011, 82, 1297-1316.

11. “KMnO₄-Mediated Oxidation as a Continuous Flow Process”
J. Sedelmeier*, I.R. Baxendale, S.V. Ley*, M. Baumann* Org. Lett. 2010, 12, 3618-3621.

10. “A Multiple Microcapillary Reactor for Organic Synthesis”
C.H. Hornung, B. Hallmark, M. Baumann, I.R. Baxendale, S.V. Ley*, P. Hester, P. Clayton, M.R. Mackley* Ind. Eng. Chem. Res. 2010, 49, 4576-4582.

9. “Continuous Flow Synthesis of 3-Nitropyrrolidines via Dipolar Cycloadditions”
M. Baumann, I.R. Baxendale, S.V. Ley* Synlett 2010, 749-752.

8. “Development of Fluorination Methods using Continuous-Flow Microreactors”
M. Baumann, I.R. Baxendale, L.J. Martin, S.V. Ley*Tetrahedron 2009, 65, 6611-6625.

7. “New Opportunities for Advancing Organic Synthesis and Flow Based Chemical Processing.”
M. Baumann,I.R. Baxendale, J.J. Hayward, M.D. Hopkin, J. Jin, M.O. Kitching, S. Lanners, S.V. Ley*, N. Nikbin-Roudsari, C.D. Smith, C.J. Smith, L. TamboriniJ. Labelled Compd. and Pharmaceuticals 2008, 51, 252-253.

6. “The Use of Diethylaminosulfur-Trifluoride (DAST) for the Fluorination in a Continuous Flow Reactor.”                        
M. Baumann, I.R. Baxendale, S.V. Ley*Synlett 2008, 14, 2111-2114.

5. “A Modular Flow Reactor for Performing Curtius Rearrangements as a Continuous Flow Process”
M. Baumann, I.R. Baxendale, S.V. Ley*, N. Nikbin, C.D. Smith, J.P. Tierney Org. Biomol. Chem. 2008, 6,1577-1586.

4. “Azide Monoliths as Convenient Reactors for Efficient Curtius Rearrangement Reactions”
M. Baumann, I.R. Baxendale, S.V. Ley*, N. Nikbin, C.D. Smith Org. Biomol. Chem. 2008, 6, 1587-1593.

3. “Tagged Phosphine Reagents to Assist Reaction Work-up by Phase-switched Scavenging Using a Modular Flow Reactor”
C.D. Smith, I.R. Baxendale, G.K. Tranmer, M. Baumann, S.C. Smith, R.A. Lewthwaite, S.V. Ley* Org. Biomol. Chem. 2007, 5, 1562-1568.

2. “Fully Automated Continuous Flow Synthesis of 4,5-Disubstituted Oxazoles”
M. Baumann, I.R. Baxendale, S.V. Ley*, C.D. Smith, G.K. Tranmer Org. Lett. 2006, 8, 5231-5234.

1. “Solvent Engineering Substantially Enhances the Chemoenzymatic Production of Surfactin.“
B. Wagner, S.A. Sieber, M. Baumann, M.A. Marahiel* ChemBioChem 2006, 595-597.