Inline purification in continuous flow synthesis – opportunities and challenges

Beilstein J. Org. Chem. 2022, 18, 1720–1740
DOI: 10.3762/bjoc.18.182
García-Lacuna J, Baumann M*.

Consecutive photochemical reactions enabled by
a dual flow reactor coil strategy

Chem. Commun., 2022, 58, 13274.
DOI: 10.1039/d2cc05601a
Crawford R, Di Filippo M, Guthrie D, Baumann M*.

Photochemical Synthesis of Pyrazolines from Tetrazoles in Flow

SynOpen. 2022,
DOI: 10.1055/a-1995-1859
Burke A, Spiccio S, Di Filippo M et al.

Synthesis and biological evaluation of fluoro-substituted cationic and neutral antibiotic NHC* silver derivatives of SBC3

J. Organomet. Chem. 2022, 976, 122436,
Beato Z, Ryan B, Müller-Bunz H, Baumann M*, Tacke M.

Flow synthesis of oxadiazoles coupled with sequential in-line extraction and chromatography
Beilstein J. Org. Chem2022, 18, 232–239,
Donnelly K and Baumann M.

Protein domain-based prediction of drug/compound–target interactions and experimental validation on LIM kinases
PLoS Computational Biology 202117, 11, DOI:
Doğan T, Güzelcan E A, Baumann M, Koyas A, Atas H, Baxendale I R, Martin M, Cetin-Atalay  R

Continuous Flow Synthesis of Anticancer Drugs
Molecules 202126, 6992, DOI:
Di Filippo M and Baumann M.

Synthesis of 2H-indazoles via the Cadogan reaction in batch and flow mode
Tetrahedron Lett., 2021, 86, 153522, DOI: 10.1016/j.tetlet.2021.153522
Duffy M, Di Filippo M and Baumann M.

Scalability of photochemical reactions in continuous flow mode
Journal of Flow Chemistry, 2021, 11, 223–241,
DOI: 10.1007/s41981-021-00168-z
Donnelly K and Baumann M.

Forgotten and forbidden chemical reactions revitalised through continuous flow technology Org. Biomol. Chem., 2021, 86, 20, 14199–14206 DOI: 10.1039/D1OB01452H
Bonner A, Loftus A, Padgham A.C and Bauman M.

Discovery of a photochemical cascade process by flow-based interception of isomerising alkenes Chem. Sci.202112, 9895-9901, DOI:  10.1039/D1SC02879K   Di Filippo M, Trujillo C, Sánchez-Sanz G, Batsanov A.S and Baumann M.

A continuous flow synthesis of [1.1.1]propellane and bicyclo[1.1.1]pentane derivatives
Chem. Commun.2021, 57, 2871-2874 DOI:
Donnelly K  and  Baumann M.

Highlighted by SynFacts: Synfacts 2021, 17, 0715

Coupling biocatalysis with high-energy flow reactions for the synthesis of carbamates and β-amino acid derivatives Beilstein J. Org. Chem., 2021, 17, 379–384 
Leslie A., Moody T.S, Smyth M, Wharry S and Baumann M.

Development of a Continuous Photochemical Benzyne-Forming Process
SynOpen, 2021, 5, 1, 29-35, DOI: 10.1055/s-0040-1706016
Bracken C, Batsanov A.S, Baumann M.

Continuous flow synthesis and antimicrobial evaluation of NHC* silver carboxylate derivatives of SBC3 in vitro and in vivo

Metallomics, 2021, 2, 13, mfaa011, DOI: 10.1093/mtomcs/mfaa011
O’Beirne C, E Piatek M.E, Fossen J, Müller-Bunz H, Andes D.R, Kavanagh K, Patil S.A , Marcus Baumann M, Tacke M.

Tandem Continuous Flow Curtius Rearrangement and Subsequent Enzyme-Mediated Impurity Tagging
Organic Process Research & Development, 2021, 25, 3, 452–456 DOI:
Baumannn M, Leslie A, Moody T.S, Smyth M, and Wharry S.

Functional Group Interconversion Reactions in Continuous Flow Reactors 
Current Organic Chemistry, 2021, 25, 19, 2217 – 2231, DOI: 10.2174/1385272825666210610154414 
Leslie A, Joseph A.M, Baumann M.